Alex Manning and her friends decide to visit the local video arcade known as "Dante's Inferno" where a new virtual reality arcade game called "Arcade" is being test marketed by a computer company CEO. However, it soon becomes clear that the teenagers who lose are being imprisoned inside the virtual reality world by the central villain "Arcade" and takes over their minds.
A hardened New Orleans cop, Dave Robicheaux, finally tosses in the badge and settles into life on the bayou with his wife. But a bizarre plane crash draws him back into the fray when his family is viciously threatened.